Hi Don & emay68,
I'm having the same problem as emay68.
Problem: Topaz Studio v1.6.10 for Windows:
I'm experiencing the identical situation as, emay68. The UI is non-functional. Except for the "Adjustments" menu item and the "Get Support" item under the "Help" menu section all other menu items are greyed-out. Also, like emay68 there is no way to log on.
I have experienced this on two very high end gaming machines both running Windows 10 64-bit ver. 1709 (Creators update), one a desktop and another on my notebook. Both machines are running high end graphics cards and are OpenGL 3.3 compatible with the latest NVIDIA drivers installed.
Attempted Solutions & Results:
1. Desktop computer. I uninstalled, rebooted machine and re-installed the program.
Result: failed - UI still non-functional.
Desktop computer. I then uninstalled TS and in addition deleted the Local/AppData/Topaz Labs/Topaz Studio directory.
Result: failed - UI still non-functional
Notebook computer: I installed TS on my notebook and encountered the identical TS UI problem.
Hope this helps,
.: garth :.