AI Clear should be used at the beginning of your workflow whenever possible. When processing in an HDR program, the noise pattern that AI clear looks for is processed as well.
This entire product was trained on Jpegs and Raw images directly out of camera without any processing, so that use case is going to give you the best result. It doesn't mean that it won't work on other images, or processed images, just that you're not going to see best results.
Hope that helps, i've been working on the update, i'll be working on additional content once we get this beta version feedback etc implemented. I appreciate patience, the entire company is very small and the only person available to work on training content is myself. Working as fast as I can on those, if anyone knows a reliable cloning facility i'd love to have another couple of me